5 Simple Techniques For https://www.ceesdekker.net
5 Simple Techniques For https://www.ceesdekker.net
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Nanotechnology delivers An array of possibilities to lead to biology. In this article I will current illustrations where by nanofabrication – the ability to make confined constructions with dimensions at will – is used to examine the biophysics of solitary molecules and cells. I'll existing some examples from our lab:
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I can hardly imagine how I, for a geneticist, would be able to discover elementary physics, not to mention contend at the highest. How did you go about this?
2010, created a fresh way (‘wedging transfer’) to control nanostructures; initially report of DNA translocation as a result of graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
All parameters had been precisely the same for every panel in this video clip, apart from the Preliminary placement on the 6hb rod (revealed in blue) over the nanopore. Simulations that terminated early because of translocation from the rod throughout the pore are marked by a grey qualifications.
Example (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in gray, the rim on the pore is highlighted in red, plus a 3D rendering from the movement of the DNA rod is exhibited.
The rotors harness Strength from a nanoscale h2o and ion stream which is generated by a static chemical or electrochemical probable gradient while in the nanopore, which can be established via a salt gradient or utilized voltage, respectively. These artificial nanoengines self-Manage and function autonomously in physiological conditions, suggesting tips on how to setting up energy-transducing motors at nanoscale interfaces.
There was one particular trouble though — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule level, conducting polymers had been truly not this kind of excellent conductors, which was fairly disappointing. We As a result broadened our look at to test to seek out far more promising molecules.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
‘That fears the synthetic mobile, as part of the Dutch BaSyC initiative. Craig Venter seemed major-down in Individuals times and discovered about five hundred genes that happen to be minimally needed for your performing cell. We https://www.ceesdekker.net wish to glimpse bottom-up: how do we go from the couple of molecules to a whole Organic system?
Permit’s initially glimpse back in the mean time if you made a decision to change your concentration from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
The biophysicist from Delft – who continues to be Probably the most cited scientists in the Netherlands For some time – usually takes his accountability to lead towards the explanation and popularisation of his do the job for the border of physics and biology particularly significantly and routinely appears from the media; if not to discuss his work, then about the connection among science and his Christian faith.